Improving working memory and pain inhibition in older persons using transcranial direct current stimulation.

TitleImproving working memory and pain inhibition in older persons using transcranial direct current stimulation.
Publication TypeJournal Article
Year of Publication2019
AuteursDeldar, Z, Rustamov, N, Blanchette, I, Piché, M
JournalNeurosci Res
Volume148
Pagination19-27
Date Published2019 Nov
ISSN1872-8111
KeywordsAdult, Aged, Aged, 80 and over, Female, Humans, Inhibition, Psychological, Male, Memory, Short-Term, Middle Aged, Nociceptive Pain, Pain Management, Prefrontal Cortex, Transcranial Direct Current Stimulation
Abstract

The aim of the present study was to examine whether transcranial Direct Current Stimulation (tDCS) could enhance working memory and pain inhibition in older persons. Fifteen volunteers (7 women, 8 men; mean ± SD: 64 ± 4.4 y.o.) participated in two tDCS sessions during which an n-back task was performed with two levels of working memory load, while painful stimulation was delivered at the ankle. The experiment included five within-subject counterbalanced conditions (pain alone and 0-back or 2-back with or without pain) performed twice during each session. Compared with the pre-tDCS baseline, anodal tDCS decreased response times and improved pain inhibition by working memory in the 2-back condition (p < 0.01), but not in the 0-back or pain alone conditions, while sham tDCS produced no effect (all p > 0.3). These results indicate that working memory and pain inhibition can be improved by tDCS in older persons.

DOI10.1016/j.neures.2018.12.007
Alternate JournalNeurosci. Res.
PubMed ID30615905