Getting Too Old Too Quickly for Their Job: Senescent Glial Cells Promote Neurodegeneration.

TitleGetting Too Old Too Quickly for Their Job: Senescent Glial Cells Promote Neurodegeneration.
Publication TypeJournal Article
Year of Publication2018
AuteursGosselin, D, Rivest, S
JournalNeuron
Volume100
Issue4
Pagination777-779
Date Published2018 Nov 21
ISSN1097-4199
Abstract

In a provocative study recently published in Nature, Bussian et al. (2018) report that in tauopathies, glial cells, but not neurons, may be prone to enter cell senescence. Importantly, eliminating senescent glial cells preserves neuronal functions and prevents cognitive decline.

DOI10.1016/j.neuron.2018.11.006
Alternate JournalNeuron
PubMed ID30465763