Comorbid Insomnia and Sleep Apnea: mechanisms and implications of an underrecognized and misinterpreted sleep disorder.

TitleComorbid Insomnia and Sleep Apnea: mechanisms and implications of an underrecognized and misinterpreted sleep disorder.
Publication TypeJournal Article
Year of Publication2021
AuteursCruz, MMeira E, Kryger, MH, Morin, CM, Palombini, L, Salles, C, Gozal, D
JournalSleep Med
Volume84
Pagination283-288
Date Published2021 08
ISSN1878-5506
KeywordsDisorders of Excessive Somnolence, Humans, Sleep, Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders, Sleep Wake Disorders
Abstract

Sleep-disordered breathing (SDB) and insomnia have long been recognized as important sleep disrupters often associated with increased morbidity and mortality. Although they are often seen as divergent conditions, mainly because their cardinal symptoms (excessive daytime sleepiness, and sleep loss) differ, these two sleep disorders present with many common symptoms, which may hinder diagnosis and treatment. In addition to possible bidirectional pathways between SDB and insomnia, other factors such as circadian timing may play a role. In this paper, we review the mechanisms, differential clinical aspects, and implications of Comorbid Insomnia and Sleep Apnea, sometimes termed COMISA.

DOI10.1016/j.sleep.2021.05.043
Alternate JournalSleep Med
PubMed ID34214960