Amygdala-driven apnea: A breath of fresh air in respiratory neurobiology.

TitleAmygdala-driven apnea: A breath of fresh air in respiratory neurobiology.
Publication TypeJournal Article
Year of Publication2022
AuteursKinkead, R, Gagnon, M, Carrier, M-C, Fournier, S, Ambrozio-Marques, D
JournalBiol Psychol
Pagination108307
Date Published2022 Mar 10
ISSN1873-6246
Abstract

The amygdala is mainly known for its role in the pathogenesis of anxiety and the initiation of fear responses. However, there is growing evidence showing that the amygdala's ability to respond to internal stimuli such as CO is limited, thereby challenging its role in the brain-behavior relationship. Based on these results and the strong inhibitory connections between the central nucleus of the amygdala and key brainstem areas regulating the reflexive respiratory responses to CO, Feinstein et al. propose amygdala-driven apnea as a novel mechanism in the chemoreceptive origin of anxiety.

DOI10.1016/j.biopsycho.2022.108307
Alternate JournalBiol Psychol
PubMed ID35278529