Structural correlates of spoken language abilities: A surface-based region-of interest morphometry study.

TitleStructural correlates of spoken language abilities: A surface-based region-of interest morphometry study.
Publication TypeJournal Article
Year of Publication2015
AuthorsRoehrich-Gascon, D, Small, SL, Tremblay, P
JournalBrain Lang
Volume149
Pagination46-54
Date Published2015 Oct
ISSN1090-2155
KeywordsAdult, Brain Mapping, Cerebral Cortex, Humans, Magnetic Resonance Imaging, Neuropsychological Tests, Parietal Lobe, Prefrontal Cortex, Semantics, Speech, Young Adult
Abstract

Brain structure can predict many aspects of human behavior, though the extent of this relationship in healthy adults, particularly for language-related skills, remains largely unknown. The objective of the present study was to explore this relation using magnetic resonance imaging (MRI) on a group of 21 healthy young adults who completed two language tasks: (1) semantic fluency and (2) sentence generation. For each region of interest, cortical thickness, surface area, and volume were calculated. The results show that verbal fluency scores correlated mainly with measures of brain morphology in the left inferior frontal cortex and bilateral insula. Sentence generation scores correlated with structure of the left inferior parietal and right inferior frontal regions. These results reveal that the anatomy of several structures in frontal and parietal lobes is associated with spoken language performance. The presence of both negative and positive correlations highlights the complex relation between brain and language.

DOI10.1016/j.bandl.2015.06.004
Alternate JournalBrain Lang
PubMed ID26185048
PubMed Central IDPMC4587378
Grant ListR01 DC003378 / DC / NIDCD NIH HHS / United States