Heterogeneity of repetition abilities in logopenic variant primary progressive aphasia.

TitleHeterogeneity of repetition abilities in logopenic variant primary progressive aphasia.
Publication TypeJournal Article
Year of Publication2021
AuthorsMacoir, J, Martel-Sauvageau, V, Bouvier, L, Laforce, R, Monetta, L
JournalDement Neuropsychol
Volume15
Issue3
Pagination405-412
Date Published2021 Jul-Sep
ISSN1980-5764
Abstract

The differential diagnosis of primary progressive aphasia (PPA) is challenging due to overlapping clinical manifestations of the different variants of the disease. This is particularly true for the logopenic variant of PPA (lvPPA), in which such overlap was reported with regard to impairments in repetition abilities. In this study, four individuals with lvPPA underwent standard neuropsychological and language assessments. The influence of psycholinguistic variables on their performance of in word, nonword and sentence repetition tasks was also specifically explored. Some level of heterogeneity was found in cognitive functions and in language. The four participants showed impairment in sentence repetition in which their performance was negatively affected by semantic reversibility and syntactic complexity. This study supports the heterogeneity of lvPPA with respect to the cognitive and linguistic status of participants. It also shows that sentence repetition is influenced not only by length, but also by semantic reversibility and syntactic complexity, two psycholinguistic variables known to place additional demands on phonological working memory.

DOI10.1590/1980-57642021dn15-030014
Alternate JournalDement Neuropsychol
PubMed ID34630930
PubMed Central IDPMC8485642