Freesurfer cortical normative data for adults using Desikan-Killiany-Tourville and ex vivo protocols.

TitleFreesurfer cortical normative data for adults using Desikan-Killiany-Tourville and ex vivo protocols.
Publication TypeJournal Article
Year of Publication2017
AuthorsPotvin, O, Dieumegarde, L, Duchesne, S
Corporate AuthorsAlzheimer's Disease Neuroimaging Initiative
JournalNeuroimage
Volume156
Pagination43-64
Date Published2017 Aug 01
ISSN1095-9572
Abstract

We recently built normative data for FreeSurfer morphometric estimates of cortical regions using its default atlas parcellation (Desikan-Killiany or DK) according to individual and scanner characteristics. We aimed to produced similar normative values for Desikan-Killianny-Tourville (DKT) and ex vivo-based labeling protocols, as well as examine the differences between these three atlases. Surfaces, thicknesses, and volumes of cortical regions were produced using cross-sectional magnetic resonance scans from the same 2713 healthy individuals aged 18-94 years as used in the reported DK norms. Models predicting regional cortical estimates of each hemisphere were produced using age, sex, estimated intracranial volume (eTIV), scanner manufacturer and magnetic field strength (MFS) as predictors. The DKT and DK models generally included the same predictors and produced similar R2. Comparison between DK, DKT, ex vivo atlases normative cortical measures showed that the three protocols generally produced similar normative values.

DOI10.1016/j.neuroimage.2017.04.035
Alternate JournalNeuroimage
PubMed ID28479474